Before gaining popularity in the world of professional wrestling, Mero worked as a model for L'Oréal, Pepsi, and Guess?. Along with her second husband Marc Mero, she began working for the World Wrestling Federation (WWF) in 1996. As Sable, she was one of the first WWE Divas, and she gained considerable popularity, surpassing that of her husband's. After feuding with Luna Vachon, and Jacqueline, Sable became the second WWF Women's Champion after the title was reinstated into the company. After becoming a heel and leaving the company, Mero filed a $110 million lawsuit against the company, citing allegations of sexual harassment and unsafe working conditions.
In 2003, she returned to the newly renamed World Wrestling Entertainment (WWE) where she was put into a storyline feud with Torrie Wilson, and another storyline as Vince McMahon's mistress. In 2004, she left the company to spend more time with her family.
Outside of wrestling, Mero has been featured on the cover of Playboy three times. The April 1999 issue of the magazine with her on the cover was one of the highest selling issues in Playboy history. She has also guest starred on several television series, including Pacific Blue. She also appeared in the film Corky Romano.
Rena Greek was born in Jacksonville, Florida. She was active in her youth and was interested in activities such as gymnastics, horseback riding, and softball. After winning her first beauty pageant at twelve years of age, she eventually became a model in 1990, working with companies such as L'Oréal, Pepsi, and Guess?.
Greek married Wayne W. Richardson in 1986. The couple had a daughter named Mariah in 1991. The two remained married until Richardson died in a drunk-driving accident in 1991. She met her second husband, professional wrestler and former boxer Marc Mero, who had been performing in World Championship Wrestling as "Johnny B. Badd", in 1993. Mero also had breast augmentation surgery in 1993 to increase her self-esteem. After marrying Mero in the following year, she broke into the wrestling business through the World Wrestling Federation.
Rena Mero made her World Wrestling Federation debut as Sable at WrestleMania XII in March 1996, escorting Hunter Hearst Helmsley to the ring as he took on the returning The Ultimate Warrior. Mero's first major angle as Sable involved her then real-life husband, who debuted at WrestleMania XII as "Wildman" Marc Mero. The storyline started when Marc Mero witnessed Sable being mistreated by Helmsley backstage, so Marc Mero attacked Helmsley and took Sable as his manager. She remained Mero's manager until his injury in 1997. Between 1997 and the time he returned from his injury in 1998, Sable became popular on her own. In her next storyline, a returning Marc Mero (now known as "Marvelous" Marc Mero) became jealous, refused to let Sable get any of the spotlight, and mistreated her. The duo entered into a feud with Luna Vachon and The Artist Formerly Known as Goldust, which climaxed in a match at WrestleMania XIV in March 1998. Sable delivered a superkick to Goldust and executed a "Sable Bomb", a version of the powerbomb, on Luna. She also delivered a TKO and pinned Luna to finish the match, with the crowd chanting Sable's name in the background. At the following pay-per-view event, Unforgiven in April 1998, Sable lost to Luna in an Evening Gown match after being distracted by Marc Mero.
After Marc's interference at Unforgiven, Sable came to the ring and challenged Marc to a match. Sable then kicked him in the groin and delivered a Sable Bomb to get revenge. Sable eventually broke away from "Marvelous" Marc Mero, who debuted Jacqueline as his new manager, resulting in a storyline feud between the two women. The two met in a bikini contest in July 1998 at Fully Loaded. Sable, only wearing impressions of hands painted on her exposed breasts, won the contest. The next night on Raw however, Vince McMahon disqualified Sable from the previous night's contest since she did not actually wear a bikini, and the match was then awarded to Jacqueline. In response, Sable gave McMahon the double finger. At SummerSlam, Sable and her mystery partner, federation newcomer Edge, defeated Marc Mero and Jacqueline in a mixed tag team match.
Sable and Jacqueline faced off for the newly reinstated WWF Women's Title on the September 21, 1998 edition of Raw. Jacqueline claimed the title after Marc Mero interfered. On November 15, 1998 at Survivor Series, she dropped the title to Sable, who won after powerbombing both Marc and Jacqueline during the match. During this time, Rena had a guest appearance on an episode of the USA Network show Pacific Blue. Sable then briefly entered a storyline where she was forced to play a subservient role to Vince and Shane McMahon, but the storyline was cut short.
In June 1999, Rena Lesnar quit the WWF and filed a $110 million lawsuit against the company, citing allegations of sexual harassment and unsafe working conditions. She claims to have filed the lawsuit after refusing to go topless. During the course of the lawsuit, Vince McMahon counter-sued Rena over control of the stagename "Sable". Lesnar reduced the amount she was seeking in damages, and they eventually settled out of court in August 1999. Lesnar used her real name for her appearance in the September 1999 issue of Playboy. She was the first woman in history to be given two Playboy covers in the same year. After her WWF exit, she made an on-camera appearance as an audience member on World Championship Wrestling's Nitro on June 14, 1999.
During this time, Lesnar made appearances on The Howard Stern Show and Late Night with Conan O'Brien. She also made appearances on television shows such as Relic Hunter and First Wave and in the films Corky Romano as a female bouncer and Ariana's Quest. She released her autobiography, entitled Undefeated in August 2000. She also released a comic book entitled The 10th Muse starring herself as a superhero. In May 2001, Lesnar was given an advice column on CompuServe. On November 13 and November 14, 2001, she appeared as the on-camera "CEO" of the newly formed X Wrestling Federation (XWF), but these were her only appearances with the company.
Rena, along with Brock Lesnar, appeared at several New Japan Pro Wrestling shows after her WWE release. After Rena and Marc Mero became officially divorced in 2004, she began dating Lesnar, whom she became engaged to later that year. The engagement was called off in early 2005, but they were engaged again in January 2006. They were married on May 6th, 2006. The couple have two sons together, Turk and Duke. She also has a stepdaughter, Mya, from Brock's first marriage.